| Rank | Title | USA Box Office |
| 1. | Avatar (2009) | $760,410,799 |
| 2. | Titanic (1997) | $600,779,824 |
| 3. | The Dark Knight (2008) | $533,316,061 |
| 4. | Star Wars (1977) | $460,935,665 |
| 5. | Shrek 2 (2004) | $436,471,036 |
| 6. | E.T.: The Extra-Terrestrial (1982) | $434,949,459 |
| 7. | Star Wars: Episode I - The Phantom Menace (1999) | $431,065,444 |
| 8. | Pirates of the Caribbean: Dead Man's Chest (2006) | $423,032,628 |
| 9. | Toy Story 3 (2010) | $413,913,145 |
| 10. | Spider-Man (2002) | $403,706,375 |